Everything about Hypertrophy totally explained
Hypertrophy is the increase of the size of an organ or in a select area of the tissue. It should be distinguished from
hyperplasia which occurs due to cell division increasing the
number of cells while their size stays the same; hypertrophy occurs due to an increase in the
size of cells, while the number stays the same.
Examples of hypertrophy
Muscular hypertrophy
One of the most common and visible forms of organ hypertrophy occurs in skeletal muscles in response to
strength training (known as
muscle hypertrophy). Depending on the type of training, the hypertrophy can occur through increased
sarcoplasmic volume or increased
contractile proteins.
Ventricular hypertrophy
Ventricular hypertrophy is the increase in size of the
ventricles of the
heart. Changes can be beneficial or healthy if they occur in response to
aerobic or
anaerobic exercise, but ventricular hypertrophy is generally associated with pathological changes due to
high blood pressure or other disease states.
Hypertrophy of the breasts
Gigantomastia is the extreme growth of the breasts, for example 10 pounds (5 kg) per breast and more. In severe cases it's possible for women to have breasts that weigh well in excess of 20 lb (9 kg) each. Gigantomastia can occur as a rare complication of
pregnancy, but also with the more frequently juvenile gigantomastia during
puberty (
virginal breast hypertrophy).
Hypertrophy of the clitoris
In the most pronounced cases, clitoromegaly is a symptom of intersexuality since the large clitoris resembles a penis (the different grade of genital ambiguity is commonly measured by the Prader classification ranging, in ascending order of masculinisation, from 1: Female external genitalia with clitoromegaly through 5: Pseudo-phallus looking like normal male external genitalia).
Further Information
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